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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c3da5bcd76e55bb0f42513181f021047a1ca4f3c9389528696848c7ac82c6d' 
  AND token = 'eZB2DAQXQlYOhAG24oUU8fb/mhUuEGdwT/5q2qI1cHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}