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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743e1aa6cbb46986c912850591d4c2ea73cccdabce755498f1a9af3312864ab2' 
  AND token = 'MjPWG+E5KZoZZrjW56gOi3fs822UW9ixD645kx0Nx00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}