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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7253a7a9590831f3b0eaac90ed324848aaeac1b9313998d62905d1ce341d2f0' 
  AND token = 'eS9BUqKiR4wpjoQZgca7btbOsyNxiBf3nFtYrn0Loow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}