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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39250920409edca7f68d4b42892371a4ceb0dad5220af0f574b5c843fd5eb0f' 
  AND token = 'JRWh+sHHGp9cjtzMtibXRdU2XFj9d+hTwA/xVV3OnGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}