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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1876c2241629e93c63dfe7cc3447e988bd74aaa6b2c0290d8b04b6e4bb87078a' 
  AND token = 'uJIung2c7Afdx2Z7+oJmCGx9+fe2K0ZTs5kpel1XnCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}