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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b7c5eaa5d870a9a7a4fe69e826483e99421d4f2b6d01171f12e52a9d4895227' 
  AND token = '0RalDQbRQiLr/6uRzq45Z6+ser12r5EMT8Bp59m+VHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}