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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9757d020fc1e6a22478e32efbb4b75ed0ef6dcee996d142fc76e85b55a0d39b' 
  AND token = 'Qxfy25294UrlnumhCfmdmdc2xRPzwiYcjJLHyidObYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}