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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254d0f777a15622e78af58ed03f9dafff3de3c98cc71ebea2c46f301e7df25fb' 
  AND token = 'FIZ3NPm9Zma1SF3VOjCqbrOtQQ0WXK7r0W1VM9OH/7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}