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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def28c875df42343c08c5812aa0f0fcf56212fe1bfb9ea47cd571e146844e18a' 
  AND token = 'Ty6n24seWbixPmglrTHI2BbKJs/4Az1VohLzVbEfAqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}