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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd05df1bcb4fbbc8b23379788b864fc4c39be263c840ec4eefc8115bbab4a120f' 
  AND token = '1E5uP8pbk+RQLq2+8Hw8IPmKypGG0URsexMKXjRMsx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}