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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd0d9f07c594e02d805c109b9cafb0835e712906837b07e09b9b41ff187d389' 
  AND token = '+otLPWcj1vWzysyguywhz1rdV2zYZYe/HS1/sQq9lM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}