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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac14a5c38646ac92d2ab09d4788c2f33b0e8c60e42f490f5a9f1045cea03e14' 
  AND token = 'p+geeTPf4Ev+MlAvUEQsRMotDqKlXN/83Ur3wgfFq/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}