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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b055159da31c86be564cc4a046b5af29d35d9fd3675e464f14df266565370e' 
  AND token = 'WvOQ4QFx2pTn3nCOQxWXsBSLyah62JXM0smhyQ253T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}