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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f4cd69149d3471a889b6a6ce923ac142eb7823ec92f48b95c59afbdf629239' 
  AND token = 'tIPfiBwy1UsE3x7WAL9qkl2udUH4k8UksPbk98Rz8IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}