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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fdf4964c18f1401c85200f070c289b483e8523468fe7e0d75a23e380dc75d17' 
  AND token = 'YzunJrQovjUbibJrPZIGkM7s+bys5D2DbzPjvl2Y3Dc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}