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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3ab18a5e925b365a953323f5a61094cda78a8df705212a323933e112094eed' 
  AND token = 'ps0ew4jUpRET5AUyOjD19pqrBHj7Rv3WaIWhxVePvfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}