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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f998f7e966945c586c638249d257242936b23b9960f1adf019e6ac8d149ea05' 
  AND token = 'kes1oQSQ8UmaTuS4HvJUA6Fwjf1p4F3lg9+q4oKZ0tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}