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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f374b00454ef222c5d4c73e4e134b5cf527d0264cb94f86a254f09ef976bba' 
  AND token = 'FlfQJXpNgLdxBD9LaqZBZb0WozN0ixuYvyOCjKc0ufg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}