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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5350e43ccbef61661780a32f87480ba1a54d8b528d91799ab435816fd9c5e894' 
  AND token = 'gURcV8LVy0e3X3+dt9R2FdIAAzSC9DiqLq6RDC9VXKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}