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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7733998c192b7ce9ac0dbcb02197990edc487bd4389afd8bfd6a81eb440f01bc' 
  AND token = 'P2gH1DfqwgOhMaKzvqS7m3DRBCAii9D3fAtamfl1AgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}