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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1438b3e0876a6f822bcd5322d6213b595f025dec6002ffdf29703956c13f7dce' 
  AND token = 'Ttrc/KkNJBGSPOA+vy/SSRhH9f4eCOfjMoppQEiZD6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}