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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7bdeee226c147e7a3234b46e4a3901314db988434d6ee820e915e0a01989634' 
  AND token = 'f+QVaaBd4mChMUfWhL0TOV9Mbc9en3YOs5zWCu1Px0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}