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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb1f5f722a0a35061be7e9da8e95ea691097b058ba68dd41f65f62ad171c3d7' 
  AND token = 'Efe9JVlm+4rqEFxbXlGPU67S0tdXaUuxZYchFWBh8V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}