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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc828193d8c5bbd27f090ba9495fa3f4dbf5a6bb955eea7c8df05c82568de872' 
  AND token = 'JCGYqoHTS3k/kwqmPPhwMhMhLmsxm7CLIsOrZO8rY0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}