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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b889a87be711ad54c196c4ed791a7a79fd227db4c04e5572c681e37e4a0941f7' 
  AND token = 'r94qxWor+ipk+wChZ/TGX714UPmOMs+dIuCPbjxwTbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}