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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bffd55c73b9f74f3583bf678d04051edc21cb6183e6f02a2e83ad25df01c7d0c' 
  AND token = 'AuhB/XWGwf9xFnlCuce3/kfc8XBl7IRYKZk5rLH0aL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}