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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25662c9ef7fa85739eac659685a41b6e0fa001cfc07904a306256778bef44389' 
  AND token = 'OdklqkxsfjJru85y5zE5t+ftt33491EaeM7SN4Ui8/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}