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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1caf1f124f22f78fe7e92b5d243b7568a72ab21ed73c9a4e6434741598a45aa' 
  AND token = 'xOttvxycHbJn9sLzkZeXmxzjaA6FHXXXAssEHulla/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}