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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a27343b271aca101294f9b21e809927f23a3f5c6c22b04791273068f2b2a4c' 
  AND token = 'JYjWWB+JwC82jSg17kL6baOc9dsEoQbIomYSDfwBKtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}