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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e07a34150a5d77b12a479d78594fe57f0b0cf5d9d830c20e171617ef4077335' 
  AND token = 'O0l2lykkoJXvTdSrWw3FVpUX7UV6eSpjIIiZRkOhr+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}