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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2cb1a96681b1328cb339faf18ab94e6ba69a919acfb5bc21db2e759aff7c11f' 
  AND token = 'P9h7W44w+Kyp5OoZwDeYN/H4c3YwsaqWCFmE8LyGeOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}