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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c861d7c7c7ffc695f75925fb387f47f69a9a7e462937dbb1b84c4de3085d12a5' 
  AND token = 'NTWhfbrvbA1l/GE6VcRnieQfHQky66sbA0nm6m3n/PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}