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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef6fd39d006b0cdacb1a1a41aeda61c22b90f42b9a3f845ecfa9c0208402d90' 
  AND token = '0uU9jIr9elG53QR4mhwTNOE9RWj71BW5aXTcmMSa/2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}