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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df607eec38c62f10046804d710cb3df79706d06203dd81506041fe5dc1bf1a48' 
  AND token = 'pHzlJ7PKFPoEriEHM9SbyBuBdHE0PCecyvwcl4xzWyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}