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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eef5a25b27844524ca26057e896096f55f33c59af7795992141cc5e9a2466623' 
  AND token = 'M65LbA96h03wS8CjKkEgQeXChM8HTX1WMr59mSXu/P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}