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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a50544768eed1e3b7dbeb541d2f93eddbf73cf3ce2a8e6243c20d13bd18a9b' 
  AND token = 'Mv4d8pdNaGc+irt4xy7E6vYQLfql0XPnv43yfh/jtek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}