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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fa7a3e841c1e55bb9f4884c92cc4c1fb128da67c8eb283dd888db4b325e919' 
  AND token = 'YQLoC6UCN64+9XMHwcsuzWUtlh/d/RQnnnJjxCR7NpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}