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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b9a99a9f992f9b701eb46f858db1a15725d2b967a1136a1dbb7bb7461fbbc6' 
  AND token = 'dAmCGR8RRTL1CE7GxN4MR79xZ2cJe7/mRPCYp0cSCGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}