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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da80b40adda78d3315a2ce4f7910b8862603bebaf56139c2cee4d5ae8de6cb77' 
  AND token = 'IBWPb64g45oBoxAgtku6IgzbyM2sbZZp4z2vG0s9R/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}