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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500fd00a8f6a6480d7f7df94be10f2b9bc83d1ffb80f3717b198d8460c413e3d' 
  AND token = 'KJVcSJTPUoYrbaKXD57heDKnI9+myY5AGHWjm+2g9Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}