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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '912be6312dba458aee8a1ca59a26601ebc90452cfe42dffb6ce245dd0555caf6' 
  AND token = '0PDnlotexh5RfWEtw16FTs/ldfhuFTD/eTHRE4SGbeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}