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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306598e12b7a99343a8dd176fdd646fc96ff036877f99a52e49b28870f92e0ad' 
  AND token = 'CZCBAz/QWr4W5jo/bKUOU91O8EDbGOVErHDMeCoEqCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}