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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dd24a49a3ecfab7e16a0e42391969f6c1857225e47c1c0e0dfa27c64fa2bfa1' 
  AND token = 'z3hiHo2/2YkUogUPPXhCTCXkamXUSjVSZOoMSRdfbuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}