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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484cb8d0669d98b650db34fe38e442fc5f05d95389f1dbfc47a7126d727f872b' 
  AND token = 'uWFIf6f6ZFmikfonBFXXEPu164WvTG7tcYeNdEk/Hlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}