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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e973dad91735061e1b14539467f79632c325a7acaa2dd838ef4206df847c5a' 
  AND token = 'B3zDLgM8BFoAhAt017qdd2BXtoV9K3HrhfjabiOFdSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}