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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64bafa685bdc36bcbfc40e9c05b3f9aaaf8a63fb47aa3dc6d94decffa01d5452' 
  AND token = '4kaAxt9/gG+G/uvqH44bC7pMPv1l3Jvz2YhcfVdhx+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}