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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3a64ddd8a68abca9e03b77d17a63e9cdfb86ee43b1570087a05cee05a32ec2b' 
  AND token = 'nkYXRqS0Qd6CeyVoDxjpM4Zkc73m12y3jh2Pril5Gzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}