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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d0a65f33686dfbdaf2236d4b8824a206ad2b840e449f9c3269c7ca557aff1d' 
  AND token = 'kmZCY30kZeerU4wj2BDI/AAIdQqLObB91+6waKdLryQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}