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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2204c66157ea7415965b8d073cbdb9e450b07c6a7c9847c8055b585242e30d0e' 
  AND token = 'P/sG11ezvQ/KVmHE4DBt4H+nmYJQBJE7RLCz6Wo0rCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}