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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b969789b9f19fc30859518a531f36c2a903277180c712c00884e3a794b6a75' 
  AND token = 'cpz0SfvwmQYRUSxIV6NK4GrG0Gz440wxDKflucdeWuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}